Key takeaways:
A sore throat can result from allergies, bacterial infections, or viruses that cause the common cold or flu.
There are several over-the-counter medications that can help relieve pain or itchiness from a sore throat. And if you prefer not to take medication, there are a few home remedies that can help too.
Most sore throat medications and remedies provide quick relief and can save you a trip to a healthcare provider. But if you feel like your symptoms are getting worse rather than better, see your provider to rule out a more serious infection.
Sore throats are most common during the winter months, but they can occur year round. And once you have one, most people want to figure out how to get rid of it fast. Luckily, there are many over-the-counter (OTC) medications and remedies for relieving a sore throat.
We’ll start by covering what can cause a sore throat and then share some of the best medications and home remedies to heal one. We’ll also provide recommended age ranges for medications and precautions to take if you have certain health conditions. This way, you can decide which sore throat medication might be best for you. If you decide that OTC sore throat medications are not the best option for you, there are other remedies you can try instead.
A sore throat is often caused by one of the following:
Viruses, like the ones that cause the common cold or flu
Bacteria, which causes strep throat
Allergies
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Most sore throats are caused by viruses. But sometimes bacteria cause a sore throat, and this may need antibiotic treatment. If you have a sore throat, you can ask your healthcare provider to do a swab to figure out the cause. Based on the results, they can recommend the best sore throat treatment for you.
Regardless of the cause, OTC medications and other remedies can help relieve the discomfort from a sore throat.
What are the best over-the-counter treatments for a sore throat?
There are a range of OTC treatments for a sore throat. Let’s take a closer look.
Pain relievers
There are many pain-relieving OTC medications that can help relieve a sore throat. Most of them come in both a pill and liquid form.
Popular ones include:
Acetaminophen (Tylenol)
Ibuprofen (Advil or Motrin)
Naproxen (Aleve)
Ibuprofen and naproxen belong to a group of medications called NSAIDs (nonsteroidal anti-inflammatory drugs). They relieve pain and redness by lowering inflammation and swelling.
Here are some important things to consider before taking any pain-relieving medication for a sore throat:
Children who are at least 6 months old can be given ibuprofen (Motrin) for mild to moderate pain. Ibuprofen is not recommended for children under 6 months old. For children under 2 years old, it’s best to get appropriate dosage information from a healthcare provider.
Overall, acetaminophen (Tylenol) is safe and effective for infants and children. For infants under 3 months, talk with a healthcare provider for the most appropriate dosage.
If you have other medical conditions, it’s a good idea to check with your healthcare provider before using pain relievers for a sore throat. If you have liver problems, use caution before taking acetaminophen. Likewise, if you have high blood pressure or kidney problems, talk with your healthcare provider and pharmacist before using NSAIDs.
If you’ve had an allergic reaction to aspirin or any other NSAID medication, do not use NSAIDs.
Numbing medications
Topical numbing medications are another option for a sore throat. Also known as anesthetics, these medications numb the throat to help relieve pain. OTC medications that contain numbing agents are usually available as a throat spray or lozenge.
Some of these medications include:
Chloraseptic sprays
Throat lozenges, like Cepacol or Halls
Vicks VapoCOOL throat spray
Numbing medications contain ingredients like benzocaine, menthol, and phenol to numb the throat. Keep in mind that while these medications are effective in managing a sore throat, they can numb other areas of the mouth such as the tongue or cheeks.
It’s important to note that numbing medications are not FDA approved for a sore throat. The FDA has also issued a warning that medications containing benzocaine should not be given to children under 2 years of age. This is because these products can cause oxygen levels in the blood to drop to dangerously low levels.
Demulcents
Oral demulcents work by coating the throat with a soothing film that helps with redness and pain. Examples include:
Throat lozenges
Cough drops
Sore throat and cough pops
Throat spray
These products may combine additional active ingredients. Many oral demulcents often contain a numbing agent to reduce pain and soothe the throat. Some examples of these combination medications for a sore throat include:
Glycerin and phenol (Chloraseptic Max Strength Sore Throat Spray)
Benzocaine, honey, and glycerin (Chloraseptic Warming Sore Throat Lozenges)
Menthol, honey, and glycerin (Ricola Dual Action)
Antihistamines
Antihistamines can help a sore or itchy throat, especially when it comes from allergies. These medications work by blocking the release of histamine in the body, which is a chemical that can cause allergies and allergic reactions.
Here are some examples of OTC oral antihistamines:
Diphenhydramine (Benadryl, Diphenhist)
Loratadine (Claritin)
Cetirizine (Zyrtec)
Fexofenadine (Allegra)
Levocetirizine (Xyzal)
Products that contain chlorpheniramine
Antihistamines can have side effects that may not be safe for everyone. This is particularly true for:
Adults over 65 years old
Children under 6 years old
People with glaucoma
Anyone who has difficulty urinating
It’s always a good idea to speak with a healthcare provider before taking antihistamines, especially if you have other medical conditions or take other medications.
Soothing self-care: It can take days to get relief from strep throat pain. In the meantime, home remedies and self-care practices can make you more comfortable.
Comfort foods: Certain foods and drinks can help ease — or aggravate — a painful throat. Here’s what to choose and what to avoid.
COVID sore throat: The viral illness is sometimes accompanied by a scratchy sore throat. Here’s what four people who experienced a COVID sore throat say it feels like.
Which sore throat remedies work best?
Pain relievers, numbing medications, demulcents, and antihistamines are considered some of the best medicines for a sore throat. But some people may decide that OTC medications are not the right choice for them. If this is the case for you, there are several other sore throat remedies you can consider. Some non-medication options include:
Gargling with salt water
Ice chips or popsicles
Warm fluids, like soups or herbal teas (chamomile tea may be particularly helpful)
A humidifier or cool mist vaporizer to help with dryness
Honey (only recommended for children 12 months or older)
There are additional remedies that people commonly use for a sore throat. But there’s not enough scientific evidence to know for sure how well they work. Examples include:
Echinacea
Licorice
Ginger
Marshmallow root (not to be confused with foods containing marshmallow)
As with many supplements and herbal remedies, experts don’t fully understand how safe and effective these are. While many of them are likely harmless at low doses, it’s always best to use caution. When in doubt, ask your healthcare provider or local pharmacist — especially if you take other medications.
How to prevent a sore throat
Beyond medications and remedies, there are also some steps you can take to prevent a sore throat:
Identify allergens or triggers that might be causing your throat to get worse. This way, you can avoid them in the future.
Stay away from smoke, which can cause dryness or soreness in the throat.
Wash your hands frequently and thoroughly.
Avoid people who are sick.
It’s also important to keep in mind that a sore throat can get worse. If you notice that symptoms like redness or pain worsen, talk with your healthcare provider. They can make other recommendations or prescribe medications to help treat your sore throat.
The bottom line
A sore throat — no matter its cause — is painful and irritating. Thankfully, there are many over-the-counter medications that can help. And if you prefer to avoid medications, natural remedies can be quite effective, too. These include simple things like gargling with salt water or experimenting with cool or warm fluids to see which one helps most. And if you feel like nothing is helping, or your symptoms are getting worse, it’s a good idea to see your provider to make sure you don’t need a different sore throat treatment.
References
Centers for Disease Control and Prevention. (2021). Sore throat.
Eccles, R., et al. (2017). Soothing properties of glycerol in cough syrups for acute cough due to common cold. Pharmacy.
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MedlinePlus. (2022). Ibuprofen dosing for children.
Sullivan, J. E., et al. (2011). Fever and antipyretic use in children. Pediatrics.
U.S. Food and Drug Administration. (n.d.). Medication guide for non-steroidal anti-inflammatory drugs (NSAIDs).
U.S. Food and Drug Administration. (2015). Use caution with pain relievers.
U.S. Food and Drug Administration. (2018). Safety information on benzocaine-containing products.
GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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